Abstract：Despite the extremely low density and low temperature in the interstellar medium , the chemistry therein is surprisingly active. To date, more than 200 molecules, including many organic ones, have been detected in the interstellar medium. Some of these interstellar molecules are considered prebiotic molecules as they can serve as precursors of biological molecules such as amino acids . We have developed a series of models, including cold, warm-up and shock models, to study the chemical reactions of interstellar prebiotic molecules ethanimine and caynomethanimine isomers. By comparing the calculated abundances with the observed values, we studied in detail the formation and destruction mechanism, and pointed out the physical conditions of the corresponding regions. The study can enrich our understanding of astrochemistry, and may help to answer one of the human beings' ultimate question: the origin of life on the earth.