Abstract：Strangeon is proposed to be the constituent of bulk strong matter, as an analogy of nucleon for an atomic nucleus. The nature of both nucleon matter (2 quark flavors, u and d) and strangeon matter (3 flavors, u, d and s) are controlled by the strong-force, but the baryon number of the former is much larger than that of the latter, to be separated by a critical number of A_c ~ 10^9. While micro nucleon matter (i.e., nuclei) is focused by nuclear physicists, astrophysical/macro strangeon matter could be manifested in the form of compact stars (strangeon star), cosmic rays (strangeon cosmic ray), and even dark matter (strangeon dark matter). This trinity of strangeon matter, that may impact dramatically on today's physics, will be explained in this talk.